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Targeted metabolomics suggests a probable role of the FTO gene in the kynurenine pathway in prediabetes

BACKGROUND: Genome-wide association studies have identified the alpha-ketoglutarate dependent dioxygenase gene (FTO) as the first susceptibility gene of obesity. In the present study, we utilized targeted metabolomics in an attempt to further elucidate mechanisms underlying the action of the FTO gen...

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Detalles Bibliográficos
Autores principales: Chailurkit, La-or, Chanprasertyothin, Suwannee, Thongmung, Nisakron, Sritara, Piyamitr, Ongphiphadhanakul, Boonsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231341/
https://www.ncbi.nlm.nih.gov/pubmed/35757166
http://dx.doi.org/10.7717/peerj.13612