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Bio-Oriented Synthesis of Novel (S)-Flurbiprofen Clubbed Hydrazone Schiff’s Bases for Diabetic Management: In Vitro and In Silico Studies

A new series of (S)-flurbiprofen derivatives 4a–4p and 5a–5n were synthesized with different aromatic or aliphatic aldehydes and ketones to produce Schiff’s bases and their structures were confirmed through HR-ESI-MS, (1)H, and (13)C-NMR spectroscopy. The α-glucosidase inhibitory activities of the n...

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Detalles Bibliográficos
Autores principales: Alam, Aftab, Ali, Mumtaz, Rehman, Najeeb Ur, Ullah, Saeed, Halim, Sobia Ahsan, Latif, Abdul, Zainab, Khan, Ajmal, Ullah, Obaid, Ahmad, Shujaat, Al-Harrasi, Ahmed, Ahmad, Manzoor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231348/
https://www.ncbi.nlm.nih.gov/pubmed/35745591
http://dx.doi.org/10.3390/ph15060672