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In Silico Screening and Testing of FDA-Approved Small Molecules to Block SARS-CoV-2 Entry to the Host Cell by Inhibiting Spike Protein Cleavage

The COVID-19 pandemic began in 2019, but it is still active. The development of an effective vaccine reduced the number of deaths; however, a treatment is still needed. Here, we aimed to inhibit viral entry to the host cell by inhibiting spike (S) protein cleavage by several proteases. We developed...

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Detalles Bibliográficos
Autores principales: Ozdemir, E. Sila, Le, Hillary H., Yildirim, Adem, Ranganathan, Srivathsan V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231362/
https://www.ncbi.nlm.nih.gov/pubmed/35746605
http://dx.doi.org/10.3390/v14061129