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Protective Effects of Liquiritigenin against Cisplatin-Induced Nephrotoxicity via NRF2/SIRT3-Mediated Improvement of Mitochondrial Function

Acute kidney injury (AKI) induced by cisplatin (CP), a first-line anticancer drug for chemotherapy, is common. To date, there is an urgent need to find effective treatments to reduce the nephrotoxicity caused by CP. Meanwhile, the restoration of mitochondrial dysfunction shows potential to be used a...

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Detalles Bibliográficos
Autores principales: Zhou, Meng, Dai, Yanpeng, Ma, Yong, Yan, Yi, Hua, Min, Gao, Qi, Geng, Xue, Zhou, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231399/
https://www.ncbi.nlm.nih.gov/pubmed/35744945
http://dx.doi.org/10.3390/molecules27123823