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Isotype-specific plasma cells express divergent transcriptional programs

Antibodies are produced across multiple isotypes with distinct properties that coordinate initial antigen clearance and confer long-term antigen-specific immune protection. Here, we interrogate the molecular programs of isotype-specific murine plasma cells (PC) following helper T cell-dependent immu...

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Detalles Bibliográficos
Autores principales: Higgins, Brett W., Shuparski, Andrew G., Miller, Karen B., Robinson, Amanda M., McHeyzer-Williams, Louise J., McHeyzer-Williams, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231473/
https://www.ncbi.nlm.nih.gov/pubmed/35704755
http://dx.doi.org/10.1073/pnas.2121260119