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Isotype-specific plasma cells express divergent transcriptional programs
Antibodies are produced across multiple isotypes with distinct properties that coordinate initial antigen clearance and confer long-term antigen-specific immune protection. Here, we interrogate the molecular programs of isotype-specific murine plasma cells (PC) following helper T cell-dependent immu...
Autores principales: | Higgins, Brett W., Shuparski, Andrew G., Miller, Karen B., Robinson, Amanda M., McHeyzer-Williams, Louise J., McHeyzer-Williams, Michael G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231473/ https://www.ncbi.nlm.nih.gov/pubmed/35704755 http://dx.doi.org/10.1073/pnas.2121260119 |
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