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SpyChIP identifies cell type-specific transcription factor occupancy from complex tissues

Chromatin immunoprecipitation (ChIP) is an important technique for characterizing protein–DNA binding in vivo. One drawback of ChIP-based techniques is the lack of cell type-specificity when profiling complex tissues. To overcome this limitation, we developed SpyChIP to identify cell type-specific t...

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Detalles Bibliográficos
Autores principales: Feng, Siqian, Mann, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231492/
https://www.ncbi.nlm.nih.gov/pubmed/35696584
http://dx.doi.org/10.1073/pnas.2122900119