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SpyChIP identifies cell type-specific transcription factor occupancy from complex tissues
Chromatin immunoprecipitation (ChIP) is an important technique for characterizing protein–DNA binding in vivo. One drawback of ChIP-based techniques is the lack of cell type-specificity when profiling complex tissues. To overcome this limitation, we developed SpyChIP to identify cell type-specific t...
Autores principales: | Feng, Siqian, Mann, Richard S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231492/ https://www.ncbi.nlm.nih.gov/pubmed/35696584 http://dx.doi.org/10.1073/pnas.2122900119 |
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