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Altered Tim-1 and IL-10 Expression in Regulatory B Cell Subsets in Type 1 Diabetes

BACKGROUND: Type 1 diabetes (T1D) is an autoimmune disease with a complex aetiology. B cells play an important role in the pathogenesis of T1D. Regulatory B cells (Bregs) are a subset of B cells that produce and secrete the inhibitory factor interleukin-10 (IL-10), thereby exerting an anti-inflammat...

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Detalles Bibliográficos
Autores principales: Liu, Yikai, Chen, Zhiying, Qiu, Junlin, Chen, Hongzhi, Zhou, Zhiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231524/
https://www.ncbi.nlm.nih.gov/pubmed/35754999
http://dx.doi.org/10.3389/fimmu.2021.773896