Mechanism of voltage sensing in Ca(2+)- and voltage-activated K(+) (BK) channels

In neurosecretion, allosteric communication between voltage sensors and Ca(2+) binding in BK channels is crucially involved in damping excitatory stimuli. Nevertheless, the voltage-sensing mechanism of BK channels is still under debate. Here, based on gating current measurements, we demonstrate that...

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Detalles Bibliográficos
Autores principales: Carrasquel-Ursulaez, Willy, Segura, Ignacio, Díaz-Franulic, Ignacio, Márquez-Miranda, Valeria, Echeverría, Felipe, Lorenzo-Ceballos, Yenisleidy, Espinoza, Nicolás, Rojas, Maximiliano, Garate, Jose Antonio, Perozo, Eduardo, Alvarez, Osvaldo, Gonzalez-Nilo, Fernando D., Latorre, Ramón
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231616/
https://www.ncbi.nlm.nih.gov/pubmed/35704760
http://dx.doi.org/10.1073/pnas.2204620119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231616/
https://www.ncbi.nlm.nih.gov/pubmed/35704760
http://dx.doi.org/10.1073/pnas.2204620119

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