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Mechanism of voltage sensing in Ca(2+)- and voltage-activated K(+) (BK) channels

In neurosecretion, allosteric communication between voltage sensors and Ca(2+) binding in BK channels is crucially involved in damping excitatory stimuli. Nevertheless, the voltage-sensing mechanism of BK channels is still under debate. Here, based on gating current measurements, we demonstrate that...

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Detalles Bibliográficos
Autores principales:	Carrasquel-Ursulaez, Willy, Segura, Ignacio, Díaz-Franulic, Ignacio, Márquez-Miranda, Valeria, Echeverría, Felipe, Lorenzo-Ceballos, Yenisleidy, Espinoza, Nicolás, Rojas, Maximiliano, Garate, Jose Antonio, Perozo, Eduardo, Alvarez, Osvaldo, Gonzalez-Nilo, Fernando D., Latorre, Ramón
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231616/ https://www.ncbi.nlm.nih.gov/pubmed/35704760 http://dx.doi.org/10.1073/pnas.2204620119

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