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Dystrophin missense mutations alter focal adhesion tension and mechanotransduction

Dystrophin is an essential muscle protein that contributes to cell membrane stability by mechanically linking the actin cytoskeleton to the extracellular matrix via an adhesion complex called the dystrophin–glycoprotein complex. The absence or impaired function of dystrophin causes muscular dystroph...

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Detalles Bibliográficos
Autores principales: Ramirez, Maria Paz, Anderson, Michael J. M., Kelly, Marcus D., Sundby, Lauren J., Hagerty, Anthony R., Wenthe, Sophia J., Odde, David J., Ervasti, James M., Gordon, Wendy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231619/
https://www.ncbi.nlm.nih.gov/pubmed/35700360
http://dx.doi.org/10.1073/pnas.2205536119