Subtype-specific expression of MELK is partly due to copy number alterations in breast cancer

Maternal embryonic leucine-zipper kinase (MELK) regulates cell cycle progression and is highly expressed in many cancers. The molecular mechanism of MELK dysregulation has not been determined in aggressive forms of breast cancer, such as triple negative breast cancer (TNBC). To evaluate molecular ma...

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Detalles Bibliográficos
Autores principales: Hardeman, Ashley A., Han, Yoo Jane, Grushko, Tatyana A., Mueller, Jeffrey, Gomez, Maria J., Zheng, Yonglan, Olopade, Olufunmilayo I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231703/
https://www.ncbi.nlm.nih.gov/pubmed/35749404
http://dx.doi.org/10.1371/journal.pone.0268693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231703/
https://www.ncbi.nlm.nih.gov/pubmed/35749404
http://dx.doi.org/10.1371/journal.pone.0268693

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