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Pathway importance by graph convolutional network and Shapley additive explanations in gene expression phenotype of diffuse large B-cell lymphoma

Deep learning techniques have recently been applied to analyze associations between gene expression data and disease phenotypes. However, there are concerns regarding the black box problem: it is difficult to interpret why the prediction results are obtained using deep learning models from model par...

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Detalles Bibliográficos
Autores principales: Hayakawa, Jin, Seki, Tomohisa, Kawazoe, Yoshimasa, Ohe, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231717/
https://www.ncbi.nlm.nih.gov/pubmed/35749395
http://dx.doi.org/10.1371/journal.pone.0269570