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Pathway importance by graph convolutional network and Shapley additive explanations in gene expression phenotype of diffuse large B-cell lymphoma
Deep learning techniques have recently been applied to analyze associations between gene expression data and disease phenotypes. However, there are concerns regarding the black box problem: it is difficult to interpret why the prediction results are obtained using deep learning models from model par...
Autores principales: | Hayakawa, Jin, Seki, Tomohisa, Kawazoe, Yoshimasa, Ohe, Kazuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231717/ https://www.ncbi.nlm.nih.gov/pubmed/35749395 http://dx.doi.org/10.1371/journal.pone.0269570 |
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