Trpc6 gain-of-function disease mutation enhances phosphatidylserine exposure in murine platelets

Platelets enhance coagulation by exposing phosphatidylserine (PS) on their cell surface in response to strong agonist activation. Transient receptor potential channels, including TRPC6, have been implicated in the calcium influx central to this process. Here, we characterize the effect of a Trpc6 ga...

Descripción completa

Detalles Bibliográficos
Autores principales: Boekell, Kimber L., Brown, Brittney J., Talbot, Brianna E., Schlondorff, Johannes S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231752/
https://www.ncbi.nlm.nih.gov/pubmed/35749414
http://dx.doi.org/10.1371/journal.pone.0270431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231752/
https://www.ncbi.nlm.nih.gov/pubmed/35749414
http://dx.doi.org/10.1371/journal.pone.0270431

Ejemplares similares