Increased glucocorticoid metabolism in diabetic kidney disease

AIMS: Glomerular damage indicated by proteinuria is a main symptom in diabetic nephropathy. Mineralocorticoid receptor (MR) antagonists (MRAs) are beneficial irrespective of aldosterone availability. Thus, we hypothesized an alternatively activated MR to promote glomerular damage in proteinuric diab...

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Detalles Bibliográficos
Autores principales: Ackermann, Daniel, Vogt, Bruno, Bochud, Murielle, Burnier, Michel, Martin, Pierre-Yves, Paccaud, Fred, Ehret, Georg, Guessous, Idris, Ponte, Belen, Pruijm, Menno, Pechère-Bertschi, Antoinette, Jamin, Heidi, Klossner, Rahel, Dick, Bernhard, Mohaupt, Markus G., Gennari-Moser, Carine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231809/
https://www.ncbi.nlm.nih.gov/pubmed/35749380
http://dx.doi.org/10.1371/journal.pone.0269920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231809/
https://www.ncbi.nlm.nih.gov/pubmed/35749380
http://dx.doi.org/10.1371/journal.pone.0269920

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