Stability evaluation of compounded hydroxyurea 100 mg/mL oral liquids using a novel analytical method involving chemical derivatization

This study assessed the stability of six extemporaneously compounded hydroxyurea oral liquids stored at room temperature. Hydroxyurea oral liquids (100 mg/mL) were prepared using three different mixing methods (mortar, mixer or QuartetRx) from either bulk powder, capsule content, or whole capsules....

Descripción completa

Detalles Bibliográficos
Autores principales: Coache, Daphné, Friciu, Mihaela, Bernine Marcellin, Ruth, Bonnemain, Lola, Viau, Annie, Roullin, V. Gaëlle, Forest, Jean-Marc, Leclair, Grégoire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231814/
https://www.ncbi.nlm.nih.gov/pubmed/35749410
http://dx.doi.org/10.1371/journal.pone.0270206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231814/
https://www.ncbi.nlm.nih.gov/pubmed/35749410
http://dx.doi.org/10.1371/journal.pone.0270206

Ejemplares similares