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Transcriptomic analyses implicate neuronal plasticity and chloride homeostasis in ivermectin resistance and response to treatment in a parasitic nematode

The antiparasitic drug ivermectin plays an essential role in human and animal health globally. However, ivermectin resistance is widespread in veterinary helminths and there are growing concerns of sub-optimal responses to treatment in related helminths of humans. Despite decades of research, the ge...

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Detalles Bibliográficos
Autores principales: Laing, Roz, Doyle, Stephen R., McIntyre, Jennifer, Maitland, Kirsty, Morrison, Alison, Bartley, David J., Kaplan, Ray, Chaudhry, Umer, Sargison, Neil, Tait, Andy, Cotton, James A., Britton, Collette, Devaney, Eileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232149/
https://www.ncbi.nlm.nih.gov/pubmed/35696434
http://dx.doi.org/10.1371/journal.ppat.1010545