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Transcriptomic analyses implicate neuronal plasticity and chloride homeostasis in ivermectin resistance and response to treatment in a parasitic nematode
The antiparasitic drug ivermectin plays an essential role in human and animal health globally. However, ivermectin resistance is widespread in veterinary helminths and there are growing concerns of sub-optimal responses to treatment in related helminths of humans. Despite decades of research, the ge...
Autores principales: | Laing, Roz, Doyle, Stephen R., McIntyre, Jennifer, Maitland, Kirsty, Morrison, Alison, Bartley, David J., Kaplan, Ray, Chaudhry, Umer, Sargison, Neil, Tait, Andy, Cotton, James A., Britton, Collette, Devaney, Eileen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232149/ https://www.ncbi.nlm.nih.gov/pubmed/35696434 http://dx.doi.org/10.1371/journal.ppat.1010545 |
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