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Coenzyme A-Dependent Tricarboxylic Acid Cycle Enzymes Are Decreased in Alzheimer’s Disease Consistent With Cerebral Pantothenate Deficiency

Sporadic Alzheimer’s disease (sAD) is the commonest cause of age-related neurodegeneration and dementia globally, and a leading cause of premature disability and death. To date, the quest for a disease-modifying therapy for sAD has failed, probably reflecting our incomplete understanding of aetiolog...

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Detalles Bibliográficos
Autores principales: Sang, Crystal, Philbert, Sasha A., Hartland, Danielle, Unwin, Richard. D, Dowsey, Andrew W., Xu, Jingshu, Cooper, Garth J. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232186/
https://www.ncbi.nlm.nih.gov/pubmed/35754968
http://dx.doi.org/10.3389/fnagi.2022.893159