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Structure-based electron-confurcation mechanism of the Ldh-EtfAB complex

Lactate oxidation with NAD(+) as electron acceptor is a highly endergonic reaction. Some anaerobic bacteria overcome the energetic hurdle by flavin-based electron bifurcation/confurcation (FBEB/FBEC) using a lactate dehydrogenase (Ldh) in concert with the electron-transferring proteins EtfA and EtfB...

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Detalles Bibliográficos
Autores principales: Kayastha, Kanwal, Katsyv, Alexander, Himmrich, Christina, Welsch, Sonja, Schuller, Jan M, Ermler, Ulrich, Müller, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232219/
https://www.ncbi.nlm.nih.gov/pubmed/35748623
http://dx.doi.org/10.7554/eLife.77095