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Increased Circulating Levels of CRP and IL-6 and Decreased Frequencies of T and B Lymphocyte Subsets Are Associated With Immune-Related Adverse Events During Combination Therapy With PD-1 Inhibitors for Liver Cancer

BACKGROUND: Programmed cell death protein 1/programmed death-ligand 1 (PD-1/PD-L1) immune-related adverse events (irAEs) are inevitable in patients with liver cancer. Although the incidence of severe irAEs is low, but can result in fatal consequences. To date, only a few commonly used clinical bioma...

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Detalles Bibliográficos
Autores principales: Yu, Yingying, Wang, Siyu, Su, Nan, Pan, Shida, Tu, Bo, Zhao, Jinfang, Shen, Yingjuan, Qiu, Qin, Liu, Xiaomeng, Luan, Junqing, Wang, Fu-Sheng, Meng, Fanping, Shi, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232255/
https://www.ncbi.nlm.nih.gov/pubmed/35756643
http://dx.doi.org/10.3389/fonc.2022.906824