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Synthesis of new Spiropyrazole derivatives under microwaves irradiation and docking study for inhibition the microbes and COVID-19
Synthesis of a new series of spiropyrazole derivatives using microwaves irradiation with high yield in minutes was achieved through a cycloaddition reaction of nitrile imines and arylidenes of 5-bromo-indan-1-one. The structure of the new spiropyrazoles was assured based on their available spectral...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Published by Elsevier B.V.
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232256/ https://www.ncbi.nlm.nih.gov/pubmed/35782313 http://dx.doi.org/10.1016/j.molstruc.2022.133581 |