Cargando…

A multi-omics deep learning model for hypoxia phenotype to predict tumor aggressiveness and prognosis in uveal melanoma for rationalized hypoxia-targeted therapy

Uveal melanoma (UM) represents the most common primary intraocular malignancy in adults and is characterized by aggressive behaviors and a lack of targeted therapies. Hypoxia-targeted therapy has become a promising new therapeutic strategy in tumors. Therefore, a better understanding of the tumor hy...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Jingting, Yi, Quanyong, Li, Ke, Chen, Lu, Dai, Lijun, Feng, Jiayao, Li, Yan, Zhou, Meng, Sun, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232399/
https://www.ncbi.nlm.nih.gov/pubmed/35782742
http://dx.doi.org/10.1016/j.csbj.2022.06.034