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A multi-omics deep learning model for hypoxia phenotype to predict tumor aggressiveness and prognosis in uveal melanoma for rationalized hypoxia-targeted therapy
Uveal melanoma (UM) represents the most common primary intraocular malignancy in adults and is characterized by aggressive behaviors and a lack of targeted therapies. Hypoxia-targeted therapy has become a promising new therapeutic strategy in tumors. Therefore, a better understanding of the tumor hy...
Autores principales: | Zhao, Jingting, Yi, Quanyong, Li, Ke, Chen, Lu, Dai, Lijun, Feng, Jiayao, Li, Yan, Zhou, Meng, Sun, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232399/ https://www.ncbi.nlm.nih.gov/pubmed/35782742 http://dx.doi.org/10.1016/j.csbj.2022.06.034 |
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