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Effects of pH alterations on stress- and aging-induced protein phase separation

Upon stress challenges, proteins/RNAs undergo liquid–liquid phase separation (LLPS) to fine-tune cell physiology and metabolism to help cells adapt to adverse environments. The formation of LLPS has been recently linked with intracellular pH, and maintaining proper intracellular pH homeostasis is kn...

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Detalles Bibliográficos
Autores principales: Jin, Xuejiao, Zhou, Min, Chen, Shuxin, Li, Danqi, Cao, Xiuling, Liu, Beidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232405/
https://www.ncbi.nlm.nih.gov/pubmed/35750966
http://dx.doi.org/10.1007/s00018-022-04393-0