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Effects of pH alterations on stress- and aging-induced protein phase separation
Upon stress challenges, proteins/RNAs undergo liquid–liquid phase separation (LLPS) to fine-tune cell physiology and metabolism to help cells adapt to adverse environments. The formation of LLPS has been recently linked with intracellular pH, and maintaining proper intracellular pH homeostasis is kn...
Autores principales: | Jin, Xuejiao, Zhou, Min, Chen, Shuxin, Li, Danqi, Cao, Xiuling, Liu, Beidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232405/ https://www.ncbi.nlm.nih.gov/pubmed/35750966 http://dx.doi.org/10.1007/s00018-022-04393-0 |
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