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A Population Pharmacokinetic Model of Whole-Blood and Intracellular Tacrolimus in Kidney Transplant Recipients

BACKGROUND AND OBJECTIVE: The tacrolimus concentration within peripheral blood mononuclear cells may correlate better with clinical outcomes after transplantation compared to concentrations measured in whole blood. However, intracellular tacrolimus measurements are not easily implemented in clinical...

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Detalles Bibliográficos
Autores principales: Franken, Linda G., Francke, Marith I., Andrews, Louise M., van Schaik, Ron H. N., Li, Yi, de Wit, Lucia E. A., Baan, Carla C., Hesselink, Dennis A., de Winter, Brenda C. M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232416/
https://www.ncbi.nlm.nih.gov/pubmed/35442010
http://dx.doi.org/10.1007/s13318-022-00767-8