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Aberrant APOBEC3C expression induces characteristic genomic instability in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is a well-known lethal and heterogeneous disease. Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (APOBEC) is an important mutagenic driver that has seldom been investigated in PDAC. Therefore, this study investigated the significance of APOBEC...

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Detalles Bibliográficos
Autores principales: Qian, Yunzhen, Gong, Yitao, Zou, Xuan, Liu, Yu, Chen, Yusheng, Wang, Ruijie, Dai, Zhengjie, Tasiheng, Yesiboli, Lin, Xuan, Wang, Xu, Luo, Guopei, Yu, Xianjun, Cheng, He, Liu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232547/
https://www.ncbi.nlm.nih.gov/pubmed/35750693
http://dx.doi.org/10.1038/s41389-022-00411-9