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A microfluidic optimal experimental design platform for forward design of cell-free genetic networks

Cell-free protein synthesis has been widely used as a “breadboard” for design of synthetic genetic networks. However, due to a severe lack of modularity, forward engineering of genetic networks remains challenging. Here, we demonstrate how a combination of optimal experimental design and microfluidi...

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Detalles Bibliográficos
Autores principales: van Sluijs, Bob, Maas, Roel J. M., van der Linden, Ardjan J., de Greef, Tom F. A., Huck, Wilhelm T. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232554/
https://www.ncbi.nlm.nih.gov/pubmed/35750678
http://dx.doi.org/10.1038/s41467-022-31306-3