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The influence of HLA genotype on the development of metal hypersensitivity following joint replacement

BACKGROUND: Over five million joint replacements are performed across the world each year. Cobalt chrome (CoCr) components are used in most of these procedures. Some patients develop delayed-type hypersensitivity (DTH) responses to CoCr implants, resulting in tissue damage and revision surgery. DTH...

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Detalles Bibliográficos
Autores principales: Langton, David J., Bhalekar, Rohan M., Joyce, Thomas J., Rushton, Stephen P., Wainwright, Benjamin J., Nargol, Matthew E., Shyam, Nish, Lie, Benedicte A., Pabbruwe, Moreica B., Stewart, Alan J., Waller, Susan, Natu, Shonali, Ren, Renee, Hornick, Rachelle, Darlay, Rebecca, Su, Edwin P., Nargol, Antoni V. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232575/
https://www.ncbi.nlm.nih.gov/pubmed/35761834
http://dx.doi.org/10.1038/s43856-022-00137-0