3pHLA-score improves structure-based peptide-HLA binding affinity prediction

Binding of peptides to Human Leukocyte Antigen (HLA) receptors is a prerequisite for triggering immune response. Estimating peptide-HLA (pHLA) binding is crucial for peptide vaccine target identification and epitope discovery pipelines. Computational methods for binding affinity prediction can accel...

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Detalles Bibliográficos
Autores principales: Conev, Anja, Devaurs, Didier, Rigo, Mauricio Menegatti, Antunes, Dinler Amaral, Kavraki, Lydia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232595/
https://www.ncbi.nlm.nih.gov/pubmed/35750701
http://dx.doi.org/10.1038/s41598-022-14526-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232595/
https://www.ncbi.nlm.nih.gov/pubmed/35750701
http://dx.doi.org/10.1038/s41598-022-14526-x

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