Integrating variant functional annotation scores have varied abilities to improve power of genome-wide association studies

Functional annotations have the potential to increase power of genome-wide association studies (GWAS) by prioritizing variants according to their biological function, but this potential has not been well studied. We comprehensively evaluated all 1132 traits in the UK Biobank whose SNP-heritability e...

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Detalles Bibliográficos
Autores principales: Gao, Jianhui, Espin-Garcia, Osvaldo, Paterson, Andrew D., Sun, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232605/
https://www.ncbi.nlm.nih.gov/pubmed/35750789
http://dx.doi.org/10.1038/s41598-022-14924-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232605/
https://www.ncbi.nlm.nih.gov/pubmed/35750789
http://dx.doi.org/10.1038/s41598-022-14924-1

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