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Construction of a synthetic Saccharomyces cerevisiae pan-genome neo-chromosome

The Synthetic Yeast Genome Project (Sc2.0) represents the first foray into eukaryotic genome engineering and a framework for designing and building the next generation of industrial microbes. However, the laboratory strain S288c used lacks many of the genes that provide phenotypic diversity to indus...

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Detalles Bibliográficos
Autores principales: Kutyna, Dariusz R., Onetto, Cristobal A., Williams, Thomas C., Goold, Hugh D., Paulsen, Ian T., Pretorius, Isak S., Johnson, Daniel L., Borneman, Anthony R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232646/
https://www.ncbi.nlm.nih.gov/pubmed/35750675
http://dx.doi.org/10.1038/s41467-022-31305-4