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Sizing up DNA nanostructure assembly with native mass spectrometry and ion mobility

Recent interest in biological and synthetic DNA nanostructures has highlighted the need for methods to comprehensively characterize intermediates and end products of multimeric DNA assembly. Here we use native mass spectrometry in combination with ion mobility to determine the mass, charge state and...

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Detalles Bibliográficos
Autores principales: van Dyck, Jeroen F., Burns, Jonathan R., Le Huray, Kyle I. P., Konijnenberg, Albert, Howorka, Stefan, Sobott, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232653/
https://www.ncbi.nlm.nih.gov/pubmed/35750666
http://dx.doi.org/10.1038/s41467-022-31029-5