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Detection of electrostatic molecular binding using the water proton signal

PURPOSE: Saturation transfer MRI has previously been used to probe molecular binding interactions with signal enhancement via the water signal. Here, we detail the relayed nuclear overhauser effect (rNOE) based mechanisms of this signal enhancement, develop a strategy of quantifying molecular bindin...

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Detalles Bibliográficos
Autores principales: Zhou, Yang, Bie, Chongxue, van Zijl, Peter C. M., Xu, Jiadi, Zou, Chao, Yadav, Nirbhay N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232913/
https://www.ncbi.nlm.nih.gov/pubmed/35394084
http://dx.doi.org/10.1002/mrm.29230