1,25-Dihydroxyvitamin D3 suppresses CD4(+) T-cell effector functionality by inhibition of glycolysis

In CD4(+) T helper cells, the active form of vitamin D(3), 1,25-dihydroxyvitamin D(3) (1,25D) suppresses production of inflammatory cytokines, including interferon-gamma (IFN-γ), but the mechanisms for this are not yet fully defined. In innate immune cells, response to 1,25D has been linked to metab...

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Detalles Bibliográficos
Autores principales: Bishop, Emma L., Gudgeon, Nancy H., Mackie, Gillian M., Chauss, Daniel, Roberts, Jennie, Tennant, Daniel A., Maslowski, Kendle M., Afzali, Behdad, Hewison, Martin, Dimeloe, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232967/
https://www.ncbi.nlm.nih.gov/pubmed/35322416
http://dx.doi.org/10.1111/imm.13472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232967/
https://www.ncbi.nlm.nih.gov/pubmed/35322416
http://dx.doi.org/10.1111/imm.13472

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