Cargando…

Utility based approach in individualized optimal dose selection using machine learning methods

The goal in personalized medicine is to individualize treatment using patient characteristics and improve health outcomes. Selection of optimal dose must balance the effect of dose on both treatment efficacy and toxicity outcomes. We consider a setting with one binary efficacy and one binary toxicit...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Pin, Taylor, Jeremy M. G., Boonstra, Philip S., Lawrence, Theodore S., Schipper, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233043/
https://www.ncbi.nlm.nih.gov/pubmed/35343595
http://dx.doi.org/10.1002/sim.9396