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The Magic of Linking Rings: Discovery of a Unique Photoinduced Fluorescent Protein Crosslink
[Image: see text] Fluorosubstituted tryptophans serve as valuable probes for fluorescence and nuclear magnetic resonance (NMR) studies of proteins. Here, we describe an unusual photoreactivity introduced by replacing the single tryptophan in cyclophilin A with 7-fluoro-tryptophan. UV exposure at 282...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233106/ https://www.ncbi.nlm.nih.gov/pubmed/35574633 http://dx.doi.org/10.1021/jacs.2c02054 |