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Lrwd1 impacts cell proliferation and the silencing of repetitive DNA elements

LRWD1, also known as ORCA, is a nuclear protein functioning in multiple biological processes. Using its WD40 domain LRWD1 interacts with repressive histone marks and maintains the silencing of heterochromatin regions in mammalian cells. ORCA also associates with the origin recognition complex (ORC)...

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Detalles Bibliográficos
Autores principales: Kang, Tze Zhen Evangeline, Wan, Yi Ching Esther, Zhang, Zhiguo, Chan, Kui Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233303/
https://www.ncbi.nlm.nih.gov/pubmed/35451548
http://dx.doi.org/10.1002/dvg.23475