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Mitochondrial DNA methylation profiling of the human prefrontal cortex and nucleus accumbens: correlations with aging and drug use

BACKGROUND: Despite the brain’s high demand for energy, research on its epigenetics focuses on nuclear methylation, and much of the mitochondrial DNA methylation remains seldom investigated. With a focus on the nucleus accumbens (NAcc) and the prefrontal cortex (PFC), we aimed to identify the mitoch...

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Detalles Bibliográficos
Autores principales: Huang, Chia-Hung, Chang, Man-Chen, Lai, Yung-Chun, Lin, Chun-Yen, Hsu, Cho-Hsien, Tseng, Bo-Yuan, Hsiao, Chuhsing Kate, Lu, Tzu-Pin, Yu, Sung-Liang, Hsieh, Sung-Tsang, Chen, Wei J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233363/
https://www.ncbi.nlm.nih.gov/pubmed/35752846
http://dx.doi.org/10.1186/s13148-022-01300-z