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Agonist-induced Piezo1 activation promote mitochondrial-dependent apoptosis in vascular smooth muscle cells
OBJECTIVE: Mechanical damage plays an essential role in the progression of atherosclerosis. Piezo1 is a new mechanically sensitive ion channel. The present study investigated the vascular smooth muscle cells (VSMCs) apoptosis induced by Piezo1 activation and explored its underlying mechanism. METHOD...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233385/ https://www.ncbi.nlm.nih.gov/pubmed/35751027 http://dx.doi.org/10.1186/s12872-022-02726-2 |