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Agonist-induced Piezo1 activation promote mitochondrial-dependent apoptosis in vascular smooth muscle cells

OBJECTIVE: Mechanical damage plays an essential role in the progression of atherosclerosis. Piezo1 is a new mechanically sensitive ion channel. The present study investigated the vascular smooth muscle cells (VSMCs) apoptosis induced by Piezo1 activation and explored its underlying mechanism. METHOD...

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Detalles Bibliográficos
Autores principales:	Yin, Qing, Zang, Guangyao, Li, Nannan, Sun, Chenchen, Du, Rongzeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233385/ https://www.ncbi.nlm.nih.gov/pubmed/35751027 http://dx.doi.org/10.1186/s12872-022-02726-2

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