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Alcohol-induced inhibition of bone formation and neovascularization contributes to the failure of fracture healing via the miR-19a-3p/FOXF2 axis

AIMS: Alcoholism is a well-known detrimental factor in fracture healing. However, the underlying mechanism of alcohol-inhibited fracture healing remains poorly understood. METHODS: MicroRNA (miR) sequencing was performed on bone mesenchymal stem cells (BMSCs). The effects of alcohol and miR-19a-3p o...

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Detalles Bibliográficos
Autores principales: Zhu, Daoyu, Fang, Haoyu, Yu, Hongping, Liu, Pei, Yang, Qianhao, Luo, Pengbo, Zhang, Changqing, Gao, Youshui, Chen, Yi-Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233406/
https://www.ncbi.nlm.nih.gov/pubmed/35730670
http://dx.doi.org/10.1302/2046-3758.116.BJR-2021-0596.R1