Cargando…

14-3-3θ Does Not Protect against Behavioral or Pathological Deficits in Alzheimer’s Disease Mouse Models

Alzheimer’s disease (AD) is characterized by progressive cognitive impairment associated with synaptic dysfunction and dendritic spine loss and the pathologic hallmarks of β-amyloid (Aβ) plaques and hyperphosphorylated tau tangles. 14-3-3 proteins are a highly conserved family of proteins whose func...

Descripción completa

Detalles Bibliográficos
Autores principales: Gannon, Mary, Wang, Bing, Stringfellow, Sara Anne, Quintin, Stephan, Mendoza, Itzel, Srikantha, Thanushri, Roberts, A. Claire, Saito, Takashi, Saido, Takaomi C., Roberson, Erik D., Yacoubian, Talene A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233504/
https://www.ncbi.nlm.nih.gov/pubmed/35697511
http://dx.doi.org/10.1523/ENEURO.0368-21.2022