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14-3-3θ Does Not Protect against Behavioral or Pathological Deficits in Alzheimer’s Disease Mouse Models
Alzheimer’s disease (AD) is characterized by progressive cognitive impairment associated with synaptic dysfunction and dendritic spine loss and the pathologic hallmarks of β-amyloid (Aβ) plaques and hyperphosphorylated tau tangles. 14-3-3 proteins are a highly conserved family of proteins whose func...
Autores principales: | Gannon, Mary, Wang, Bing, Stringfellow, Sara Anne, Quintin, Stephan, Mendoza, Itzel, Srikantha, Thanushri, Roberts, A. Claire, Saito, Takashi, Saido, Takaomi C., Roberson, Erik D., Yacoubian, Talene A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233504/ https://www.ncbi.nlm.nih.gov/pubmed/35697511 http://dx.doi.org/10.1523/ENEURO.0368-21.2022 |
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