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Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation
Fungal infections cause more than 1.5 million deaths annually. With an increase in immune-deficient susceptible populations and the emergence of antifungal drug resistance, there is an urgent need for novel strategies to combat these life-threatening infections. Here, we use a combinatorial screenin...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233667/ https://www.ncbi.nlm.nih.gov/pubmed/35752611 http://dx.doi.org/10.1038/s41467-022-31308-1 |