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Long-term hematopoietic stem cells as a parasite niche during treatment failure in visceral leishmaniasis
Given the discontinuation of various first-line drugs for visceral leishmaniasis (VL), large-scale in vivo drug screening, establishment of a relapse model in rodents, immunophenotyping, and transcriptomics were combined to study persistent infections and therapeutic failure. Double bioluminescent/f...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233693/ https://www.ncbi.nlm.nih.gov/pubmed/35752645 http://dx.doi.org/10.1038/s42003-022-03591-7 |