Structural mechanism of protein recognition by the FW domain of autophagy receptor Nbr1

Neighbor of BRCA1 (Nbr1) is a conserved autophagy receptor that provides cargo selectivity to autophagy. The four-tryptophan (FW) domain is a signature domain of Nbr1, but its exact function remains unclear. Here, we show that Nbr1 from the filamentous fungus Chaetomium thermophilum uses its FW doma...

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Detalles Bibliográficos
Autores principales: Zhang, Jianxiu, Wang, Ying-Ying, Pan, Zhao-Qian, Li, Yulu, Sui, Jianhua, Du, Li-Lin, Ye, Keqiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233695/
https://www.ncbi.nlm.nih.gov/pubmed/35752625
http://dx.doi.org/10.1038/s41467-022-31439-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233695/
https://www.ncbi.nlm.nih.gov/pubmed/35752625
http://dx.doi.org/10.1038/s41467-022-31439-5

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